Autophagy as a New Target: Chitosan Nanoparticles as Delivery Systems to Enhance Current Anticancer Biologics
The induction of autophagy has been shown as a prosurvival pathway in cancer cells to increase its survivability against anticancer drugs, subsequently providing ample time for the aberrant cells to develop chemoresistance. Through inhibition of autophagy, this process can be mitigated and subsequently increase the effectiveness of the chemotherapy drugs used.